Next generation sequencing articles
Methyl-seq analysis of the human ‘methylome’ provides a resource for biomarker and gene regulation research
DNA methylation is a fundamental epigenetic modification with important roles in gene regulation and expression. In an article published by Loyfer et al. [1] the authors cataloged the methylation patterns of dozens of cell-types sorted from 205 normal human tissue samples developing a comprehensive atlas of DNA. The researchers developed this comprehensive atlas via whole genome bisulfite sequencing on libraries prepared using IDT’s xGen™ Methyl-Seq DNA Library Prep Kit.
- Methyl-seq analysis of the human ‘methylome’ provides a resource for biomarker and gene regulation research
- Viral surveillance using wastewater
- A fusion gene identification strategy using CRISPR-Cas9 and long read nanopore sequencing
- CRISPR-based depletion of unwanted sequences improves targeted next generation sequencing
- Tips for designing spike-in controls for next generation sequencing analysis
- Beginner’s guide to next generation sequencing
- Targeted sequencing: Hybridization capture or amplicon sequencing?
- Using CRISPR-Cas9 technology for targeted nanopore sequencing
- Protocol tips to boost your NGS target capture success
- Multiplexed targeted next generation sequencing coverage
- ve-SEQ: An improved approach to high throughput, whole genome viral sequencing
