Archer™ IMMUNOVerse™ BCR panel
Assess clonalities, MRD, and more with a targeted RNA assay
Characterize B-cell clonalities, including isotypes and subclasses in the Fc region and somatic hypermutations within the variable regions, with targeted NGS of B-cell receptor chain RNA relevant for blood cancer and solid tumor research.
Clarify the immune repertoire with Archer IMMUNOVerse NGS Panels for RNA.
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Panel specifications
| Specifications | |
|---|---|
| Target regions | BCR heavy (IGH) and light (kappa/lambda) chains |
| Applications | Clonality, MRD, profiling, somatic hypermutation |
| Input RNA required* | 20 ng to 6 μg |
| Recommended number of reads* | 250 K to 10 M |
| Hands-on time | 3.5 hours |
| Total library prep time | 1.5 days |
| Platform compatibility | Illumina® |
| Reagent format | Lyophilized |
| Supported sample types | Blood, PBMC, bone marrow, sorted B cells, FFPE, fresh frozen tissue |
*Input mass and read requirements vary depending on type, quality, B cell content, and application.
Benefits
- Secure data—Assessing samples in-house means you retain important data for further studies, ensuring all your data remains user-owned.
- Identify more—Anchored Multiplex PCR (AMP™) chemistry amplifies effectively through hypervariable sequences and variable length fragments enabling rare clone detection, even for potentially degraded FFPE tissue.
- Clarify confidently—Archer Analysis corrects for amplification bias and sequencing errors to provide a true and reproducible measure of diversity and can be used for disease monitoring, repertoire profiling, and somatic hypermutation detection.
- Achieve efficiency—Parallel workflows across all Archer panels provides streamlined genomic characterization, while single use, reaction-sized lyophilized reagents minimize hands-on time and potential pipetting errors.
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Talk with our technical sales team. Learn how the IMMUNOVerse BCR panel can identify key genomic alterations for your research.
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