Archer™ VARIANTPlex™ MPN Focus panel
Discover myeloid proliferative neoplasm insights with a targeted DNA panel
Identify key single nucleotide variants, insertions, deletions, copy number variations, and internal tandem duplications with targeted NGS of 12 genes relevant for myeloproliferative neoplasms (MPN) research.
Detect confidently with Archer VARIANTPlex NGS Panels for DNA.
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Learn how the VARIANTPlex MPN Focus panel can identify key genomic alterations for your research.
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Panel specifications
| Specifications | |
|---|---|
| Targeted genes | 12 |
| Genomic alterations | SNVs, indels, ITDs |
| Input nucleic acid required* | ≥10 ng |
| Recommended number of reads | 800 K |
| Hands-on time | <3.5 hours |
| Total library prep time | 1.5 days |
| Platform compatibility | Illumina® |
| Reagent format | Lyophilized or liquid |
| Supported sample types | Blood, bone marrow, fresh frozen, FFPE, BMMC, PBMC |
*Input mass requirements vary depending on type and quality. Unless the tumor cellularity and sample quality are high, 50 ng of FFPE-derived nucleic acid should be considered the minimum recommendation. If input is not limiting, 200 ng is recommended.
Gene targets
Interested in adding a few genes to this panel?
Customize this NGS panel by adding any of our functionally-tested designs or create a new panel that fits your exact requirements with Assay Marketplace.
Benefits
- Detect confidently—A unique outlier detection algorithm leverages position-specific data to enable variant detection even at low allele frequencies, one of the many ways that Archer Analysis empowers you to detect confidently.
- Less QNS—Anchored Multiplex PCR (AMP™) chemistry is designed for compatibility with a wide range of sample types, including low-input and potentially degraded samples such as FFPE tissue.
- Achieve efficiency—Streamlined workflows for your lab are enabled by choice of reaction-sized lyophilized reagents or high-throughput liquid reagents, while parallel workflows across all Archer panels provide efficient genomic characterization.
- Customize content—Use Assay Marketplace to modify any panel to fit your lab’s needs or start from scratch to keep up with the pace of discovery.
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Talk with our technical sales team. Learn how the VARIANTPlex MPN Focus panel can identify key genomic alterations for your research.
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